Assessment of Predictive Confounders for the Prevalence of Breast Cancer among Iraqi Population: A Retrospective Study from Baghdad, Iraq


Özet Görüntüleme: 10 / PDF İndirme: 6

Yazarlar

  • Nadia H. Mohammed Lecturer
  • Anmar Al-Taie
  • Fadia H. Al-Sultany

Anahtar Kelimeler:

Ductal breast cancer, hormone sensitivity, Iraq, risk factors.

Özet

Although breast cancer prevalence continues to increase, mortality has been decreasing as a result of
early detection and improvement in adjuvant systemic therapy. Nevertheless, this disease required further efforts to
understand and identify the associated potential risk factors that could play a role in the prevalence of this alignancy
among Iraqi women. The objective of this study was to assess the perception of certain predictive risk factors on the
prevalence of breast cancer types among a sample of Iraqi women diagnosed with breast cancer. This was a
retrospective observational study carried out at National Cancer Research Center in College of Medicine, Baghdad
University from November 2017 to January 2018. Data of 100 patients with breast cancer whose biopsies
examined in the National Cancer Research Center were included in this study. Data were collected to structure a
detailed assessment regarding the patients’ demographic, medical and cancer records. The majority of study
participants (94%) suffered from ductal breast cancer with mean age 49.57 years. Among those women, 48.9% were
obese with body mass index (BMI) 35 kg/m2 . 68.1% of them had positive family history of breast cancer and 66%
had low parity. 40.4% had stage II ductal breast cancer followed by 25.5% with stage III. It was found that 59.6% and
68.1% had positive oestrogen receptor sensitivity and positive human epidermal growth factor (HER2/neu) receptor
sensitivity respectively. In regard to the impact of prediction of certain variables on the incidence of ductal breast
cancer, positive family history of breast cancer (P < 0.0001), low parity (P< 0.0001), stage I and II breast cancer (P =
0.02) and positive HER2/neu status (P < 0.0001) were significant predictive factors among the study participants. The
results from this study provide relevant evidence for a significant positive and potential association between certain
risk factors and the prevalence of breast cancer among Iraqi women.

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Yayınlanmış

2022-12-03

Nasıl Atıf Yapılır

Mohammed, N. H., Al-Taie, A., & H. Al-Sultany, F. (2022). Assessment of Predictive Confounders for the Prevalence of Breast Cancer among Iraqi Population: A Retrospective Study from Baghdad, Iraq . IjasJournal International Journal of Applied Sciences and Technology, 1(1). Geliş tarihi gönderen https://ijasjournal.com/index.php/ijas/article/view/1